Yes, a plane can "brake" in the air using devices called spoiler panels or "speed brakes." These are large metal flaps located on the top surface of the wings. When a pilot deploys them, they "spoil" the smooth airflow over the wing, which simultaneously decreases lift and significantly increases aerodynamic drag. This allows the aircraft to slow down or descend rapidly without picking up excessive speed. While this isn't a "friction brake" like the ones on your car wheels, it is a highly effective way to manage energy during the approach to an airport. You might feel a slight vibration or hear a "rushing air" sound in the cabin when these are used. Additionally, during the final approach, the landing gear itself creates a large amount of drag that helps slow the plane. However, the most powerful "brakes"—the wheel brakes and the thrust reversers—can only be used once the wheels have touched the ground and the aircraft's weight is firmly on the landing gear, as they require physical contact with the runway to be effective.