In 2026, it is physically impossible for a human to open a standard "plug-type" cabin door on a commercial jet at cruising altitude. This is due to the extreme pressure differential between the pressurized cabin and the thin air outside. At 35,000 feet, the internal air is pushing outward against the door with thousands of pounds of force. Because these doors must be pulled inward slightly before being swung outward, a human would need to exert the strength of a hydraulic press to overcome the pressure. While you may see rare news reports of doors being opened on regional flights at low altitudes or during descent (where the pressure is equalized), a mid-flight "blowout" or opening at high altitude is prevented by the laws of physics. However, "door plugs" (fixed panels) can fail due to structural defects, as seen in recent high-profile incidents, but this is a mechanical failure rather than a manual opening.