Yes, modern hotels have several ways to detect if you have vaped in a non-smoking room, even though vape clouds dissipate faster than tobacco smoke. In 2026, many hotels have upgraded to sophisticated "air quality sensors" (like the brand FreshAir or Wynd) that are specifically designed to detect the chemical signature of nicotine or THC vapor. These sensors are far more sensitive than traditional smoke detectors and send a real-time alert to the front desk when a violation occurs. Even without high-tech sensors, housekeeping staff are trained to look for specific "tells." Vaping leaves a unique, slightly oily or sugary residue on glass surfaces, mirrors, and fabric, and the artificial scents (like fruit or mint) can linger in the upholstery and curtains for hours. Additionally, if the vapor triggers a standard "optical" smoke detector, it can set off the entire building's fire alarm, leading to massive fines or even evacuation. If caught, you will likely be charged a "cleaning fee" ranging from $250 to $500, and in some cases, you may be added to a "Do Not Lodge" list shared among hotel chains.