You can absolutely check out of a hotel at any time before the official deadline (which is usually 11:00 AM or 12:00 PM). In fact, hotels generally appreciate early departures because it gives the housekeeping staff a "head start" on turning over the room for the next guest. If the hotel has a 24-hour front desk, you can check out in person at 4:00 AM or 6:00 AM without issue. Many modern hotels also offer "contactless" checkout via their mobile app or a key-drop box in the lobby, allowing you to leave the moment you are ready. The only potential caveat is if you are on a multi-day stay and decide to leave a day early; in that case, some hotels may charge an "early departure fee" or the full cost of the remaining night depending on their specific cancellation policy.