Yes, you can absolutely take a 50ml bottle of perfume in your hand luggage. In 2026, the standard "3-1-1" rule still applies at most international airports: you are allowed to carry liquids, aerosols, and gels in containers of 100ml (3.4 oz) or less. Since 50ml is exactly half of the allowable limit, it is perfectly fine. However, there are two important conditions: the bottle must be placed inside a single, clear, quart-sized (1-liter) resealable plastic bag along with your other travel-sized liquids (toothpaste, lotion, etc.), and the bag must be able to close completely. Even if your 50ml perfume is in a fancy, heavy glass bottle, as long as the volume printed on the label is under 100ml, it will pass through security. If you are flying through an airport with newer CT scanners, you might not even need to take the bag out of your suitcase, but the 100ml-per-bottle limit still remains the global baseline for hand-carry liquids.