No, you cannot take the Shinkansen directly from Shinjuku Station. While Shinjuku is the busiest railway station in the world, it does not have Shinkansen tracks or platforms. To catch a bullet train, you must first take a local train or subway from Shinjuku to either Tokyo Station or Shinagawa Station. If you are heading west toward Kyoto, Osaka, or Hiroshima on the Tokaido Shinkansen, Shinagawa is often the most convenient transfer, taking only about 20 minutes via the JR Yamanote Line or the JR Chuo Line. If you are heading north toward Kanazawa, Sendai, or Hokkaido, you must go to Tokyo Station. In 2026, it is a common mistake for tourists to arrive at Shinjuku expecting the high-speed tracks; however, Shinjuku serves as the primary hub for regional "Limited Express" trains like the Azusa (to the Japan Alps) or the Narita Express. For the Shinkansen, always ensure you have budgeted an extra 30 minutes to navigate the transfer to Tokyo or Shinagawa stations to catch your high-speed connection.