One can carry a duffel bag as a carry-on and as a backpack. They are ideal as gym bags, sports bags, carry-on luggage on the plane. Duffel bags for the varied purpose have different orientations.

Yes, you can wear many modern duffel bags as a backpack, but whether it is comfortable depends on the bag's design. In 2026, the "Hybrid Duffel" has become a travel staple, with popular brands like Patagonia, North Face, and Peak Design featuring hidden, padded backpack straps that can be tucked away when not in use. These bags are specifically engineered to distribute weight across both shoulders, making them ideal for navigating airports or city streets hands-free. However, if you have a traditional, single-strap "gym-style" duffel, wearing it as a backpack is not recommended; trying to sling a single long strap over both shoulders often puts uneven pressure on the spine and causes the bag to sag uncomfortably against your lower back. For travelers who value versatility, a 50L to 65L hybrid duffel is often considered the "perfect" piece of luggage because it offers the easy-access packing of a suitcase with the mobility of a backpack, though you should ensure the straps are well-padded if you plan to carry heavy loads for long periods.