You cant use an Oyster card in Manchester (or anywhere outside London).
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The Bee Network app also allows you to buy new tickets that allow you to use both buses and trams around Manchester. You can pay with either cash or a card, but you can also pay for a week's travel card (which you can upload to an igo card).
Oyster cardsYou can pay as you go to travel on bus, Tube, tram, DLR, London Overground, most Elizabeth line, IFS Cloud Cable Car and Thames Clippers River Bus services. You can also travel on most National Rail services in London and some outside London.
You can't use Oyster on the following rail services on any journey starting or finishing outside the Pay as you go area: East Midlands Trains, Grand Central, Hull Trains, Virgin Trains, or London North Eastern Railway services.
Manchester is a great place to walk around whether you walk downtown among the great local restaurants and shops or Amoskeag Riverwalk that is rich with history among the renovated mill buildings.
However, if you plan on using public transport regularly in The London area, then an Oyster Card should be the better option for you. This is because you'll be eligible to get a Railcard (which can only be connected to Oyster cards, not contactless cards) and get consistent discounts off travel in the city.