Yes, pilots are allowed to carry personal Epipens if they have a documented medical need, but the underlying condition (such as a severe allergy) must be disclosed to and cleared by an Aviation Medical Examiner (AME). For a pilot to maintain their medical certificate, the FAA (or relevant national aviation authority) must be satisfied that the allergy does not pose a risk of sudden incapacitation during flight. In 2026, there is also a significant shift in onboard medical equipment; following the FAA Reauthorization Act of 2024, commercial airlines are now required to include epinephrine in a user-friendly format—such as an auto-injector (Epipen)—in their onboard Emergency Medical Kits (EMK). Previously, many kits only contained vials and syringes, which required a trained medical professional to administer. This change ensures that if a passenger or a crew member experiences anaphylaxis mid-flight, the life-saving medication is readily available and can be administered by non-medical personnel, including flight attendants, significantly improving safety for those with severe allergies.