Bipolar disorder responds positively to a set sleep routine. The same bed with the same getting to sleep ritual may be boring, but our brains love it. Travel disrupts our sleep habits and this alone can cause mood swings.
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Tourists on religious or historical trips can also suddenly exhibit symptoms of psychosis. In this case, travellers become 'intoxicated' and overwhelmed by their surroundings. This can cause travellers to become detached from reality and can lead to delusional thoughts and behaviours.
Dromomania was a historical psychiatric diagnosis whose primary symptom was uncontrollable urge to walk or wander. Dromomania has also been referred to as traveling fugue. Non-clinically, the term has come to be used to describe a desire for frequent traveling or wanderlust.