Yes, the TSA can open a Samsonite lock without damaging it, provided the lock is "TSA-Approved." Most modern Samsonite luggage comes equipped with integrated locks that feature a small red diamond logo, indicating they are part of the Travel Sentry system. These locks allow TSA agents at security checkpoints to use "universal master keys" to open your bag for inspection if the X-ray reveals a suspicious item. If you use a non-TSA approved lock, agents are legally authorized to cut or break the lock to access the contents, and the airline or TSA is not liable for the damage. In 2026, Samsonite has also introduced "Biometric" and "Bluetooth" smart locks on their high-end lines; even these are designed with a manual TSA key override. For a "pro-traveler," using a TSA-approved lock is a high-value security measure that ensures your belongings remain protected from opportunistic theft while remaining accessible to authorized federal safety personnel.