That depends on what you mean by “do LA” and how you prioritize your time.
Can you see the highlights and get a great taste of LA in 5 days? Absolutely. Can you see and do everything LA has to offer in 5 days? No way.
Five days is a solid amount of time for a first visit. You’ll need to be strategic, as LA is a massive, sprawling region (it’s not a walkable downtown with everything close by). Traffic is a major factor, so you must group activities by geographic area.
Here’s a realistic, optimized 5-day itinerary framework:
Never plan to go from Santa Monica to Downtown to Hollywood in one day. You’ll spend it all in traffic.
Day 1: Hollywood & Central LA Morning: Walk the Hollywood Walk of Fame (manage expectations—it’s a busy sidewalk), see the TCL Chinese Theatre (hand/footprints), and the Dolby Theatre. Afternoon: Explore the Academy Museum of Motion Pictures (highly recommended) or the Los Angeles County Museum of Art (LACMA) and the La Brea Tar Pits next door. Evening: Catch a show at the Hollywood Bowl (if scheduled) or have dinner and see the vibrant scene on Sunset Boulevard.
Day 2: The Beaches (Santa Monica & Venice) Morning: Start at Santa Monica Pier (ride the Ferris wheel), explore Palisades Park and the Third Street Promenade for shopping