Yes, you can absolutely fit 7 days of clothing in a standard carry-on by utilizing "capsule wardrobe" principles and packing cubes. The secret is to limit yourself to three pairs of shoes (one worn, two packed) and a "3-bottom, 7-top" rule where every item coordinates. Using compression packing cubes can reduce the volume of your clothes by up to 30%, while "rolling" instead of "folding" minimizes wrinkles and maximizes space. For 2026 travelers, a peer-to-peer "hack" is to wear your bulkiest items—like a heavy jacket or boots—on the plane to save internal suitcase real estate. If you are worried about freshness, packing a few laundry detergent sheets allows you to do a quick "sink wash" of socks or t-shirts midway through the week. With a bit of discipline and the right modular bag, a 22" carry-on is more than enough for a week-long getaway without the need for checked baggage.