We recommend avoiding sports for in the first 72 hours following a sprained ankle. Can you fly with a sprained ankle? You can fly with sprained ankle. Remember to keep it elevated and wear a bandage to help with compression.
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The usual risk of swelling is increased in travelers with extremity fractures that cannot be kept elevated in the aircraft. Furthermore, the hypoxic environment causes venodilation, leading to increased venous pooling and increasing the risk of swelling and compartment syndrome.
If you have swelling in only one leg and also have leg pain, seek prompt medical care. If you're at increased risk of blood clots, talk with your health care provider before flying. You may be at increased risk of blood clots if you recently had major surgery or you take birth control pills, for example.
Anyone with injuries where air has been trapped, because of the basic laws of physics and, more specifically, Boyle's Law, Calavan said, is at a higher risk of pain and injury inflight than others. “The biggest issue are those conditions that occur that have the possibility of trapped air.
Airlines reserve the right to waive off any applicable penalties at their discretion. If you would like to cancel your flight due to medical reasons, please contact the airline directly with a copy of your medical certificate requesting them to waive any applicable cancellation fees.