Can you fly with SSRI?

The SSRI pathway only allows consideration for pilots who take one of four SSRIS: fluoxetine (Prozac), citalopram (Celexa), escitalopram (Lexapro), or sertraline (Zoloft).



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Pharmaceutical Considerations: The use of a psychotropic drug is disqualifying for aeromedical certification purposes – this includes all antidepressant drugs, including selective serotonin reuptake inhibitors (SSRIs).

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If you aren't sure whether your medication falls into one of these categories, you should check with your AME:
  • Tranquilizers, such as but not limited to Valium, Librium, Ativan.
  • Most antidepressants. ...
  • Opiates, such as Morphine, Codeine, Lortab, Percodan, Oxycontin.
  • Muscle relaxants, such as Soma, Sonata, Flexeril.


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Some of the medications that can interact with some SSRIs include:
  • non-steroidal anti-inflammatory drugs (NSAIDs) – a common type of painkiller that includes ibuprofen, diclofenac or naproxen.
  • antiplatelets – a type of medication used to prevent blood clots, such as low-dose aspirin and clopidogrel.


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It's important not to miss any of your doses, as this could make your treatment less effective. You may also get withdrawal symptoms as a result of missing a dose of the medicine.

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An interaction between grapefruit and some medications may result in adverse side effects hence why the fruit is among the food to be avoided while taking antidepressants. Due to the high levels of the medicine in your body, you may start experiencing symptoms similar to overdose side effects.

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Medication is usually screened by X-ray; however, if a passenger does not want a medication X-rayed, he or she may ask for a visual inspection instead. This request must be made before any items are sent through the X-ray tunnel.

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Declare all drugs, medicinals, and similar products to the appropriate CBP official; Carry such substances in their original containers; Carry only the quantity of such substances that a person with that condition (e.g., chronic pain) would normally carry for his/her personal use; and.

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Drinking alcohol while taking antidepressants is generally not recommended because both of these substances can make you drowsy, less alert, and uncoordinated. When taken together, those effects are increased.

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