Yes, it is possible to get Global Entry with a 20-year-old DUI, but approval is not guaranteed as the program has "sole discretion" to reject anyone not deemed a "low-risk traveler." CBP background checks have no time limit and will definitely see an arrest from two decades ago. The general rule in 2026 is that a single, non-violent misdemeanor (like an old DUI) is often overlooked if you have a completely clean record since then and provide all court disposition documents during your interview. However, multiple DUIs or any felony-level conviction will lead to an automatic permanent denial. The best strategy is to be 100% honest on your application; "forgetting" to mention it is considered a fraudulent statement and is the number one reason for instant rejection. If denied, you can appeal to the CBP Ombudsman to argue that the 20-year-old incident does not reflect your current risk level.