Technically yes, but in 2026, the "gold standard" advice is to use a soft-sided, squashable duffel bag without a rigid frame or wheels. This is because many safari lodges are reached via small "bush planes" (like a Cessna Caravan) where the luggage pods are extremely cramped and irregular in shape. A hard-shell "spinner" suitcase cannot be squashed to fit and may be denied boarding or require you to pay for an extra seat to accommodate the bag. Furthermore, most small aircraft have a strict 15kg (33lb) total weight limit per person, including hand luggage. If you are staying at a luxury lodge that offers daily laundry service (common in 2026), you only need about 3 or 4 changes of neutral-toned clothing. A high-value tip is to leave your main suitcase at a "base hotel" in a city like Nairobi or Johannesburg and take only a small, soft "safari bag" into the bush.