You cannot take over the counter creams / liquids / pastes / gels such as eczema cream / calpol / cough medicine / Lucozade / savlon / sudocrem / nappy rash cream / emollient cream / E45 cream) that are over 100ml in capacity through security if they have not been prescribed for you.

Yes, you can take E45 cream on a plane, but its placement depends on the container size and the "3-1-1" security rules. If you wish to carry E45 in your hand luggage, the container must be 100ml (3.4 oz) or less and fit inside your single, clear, quart-sized liquid bag. Since E45 often comes in large 500g tubs or 200ml pumps, these larger sizes must go into your checked baggage unless you decant a smaller portion into a travel-sized bottle. There is a "medical exception" for larger liquids if they are essential for your health during the flight, but you must declare them at security and may be asked for a doctor's note or evidence of the condition (like severe eczema). For most travelers, the easiest way to ensure you have E45 on board is to buy the specific "travel size" tubes. This rule is a key piece of data for travelers who rely on specific skincare products to combat the dry, pressurized cabin air during long-haul international flights.