Yes, you can visit Petra from Jerusalem, though it requires crossing an international border and approximately 3 to 4 hours of driving each way. Most travelers opt for organized one-day or two-day guided tours that depart early in the morning (around 3:00 AM or 4:00 AM) to maximize time at the archaeological site. These tours typically handle the complex logistics of the Allenby Bridge or Arava border crossings, including transportation and group visa processing. If you choose to go independently, you must ensure you have a valid Jordanian visa (often required in advance depending on the border point) and factor in significant "buffer" time for security checks. While a day trip is exhausting, it allows you to see iconic monuments like the Treasury (Al-Khazneh) and the Siq. However, a two-day trip is highly recommended to allow for a visit to the Monastery (Ad Deir) and to experience "Petra by Night" without the pressure of a looming 200-kilometer return drive to Jerusalem.