Not all hotels will have distilled water readily available, and depending on where you are staying, you also may not be able to purchase it in stores.
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If distilled or filtered water is unavailable, you can consider using bottled water as an alternative. Look for bottles labeled as “distilled” or “purified” to help minimize mineral content. However, keep in mind that not all bottled waters are created equal, and some may still contain minerals and additives.
Using bottled spring water or mineral water in your CPAP may be fine to do once or twice if you're in a pinch, but it's a bad habit to get into. Many kinds of bottled water have a high mineral content which can lead to buildup over time, potentially damaging your motor, CPAP tubing, and water chamber.
Yet, more than three-quarters of CPAP users say they use their CPAP machine at least some of the time while traveling. “It's important to pack your CPAP machine whenever you travel, since OSA must be treated continuously, just like any other medical condition.”