The South African National Department of Health recommends that travelers practice mosquito avoidance year-round in malaria risk areas and take malaria chemoprophylaxis during September–May.
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Nigeria, the Democratic Republic of the Congo, the United Republic of Tanzania, and Niger account for about half of all such fatalities. Nigeria alone had 31.3% of the world's malaria deaths in 2021. Malaria is transmitted through mosquitoes infected with plasmodium, a single-cell parasite.
Regardless of the time of year, visitors on a Kruger safari holiday should take anti-malaria tablets and take the same precautions to prevent being bitten.