Does airplane cabin pressure affect blood pressure?
Does flying affect blood pressure? Yes it can. At high altitudes, even in a pressurised aircraft cabin, passengers are at risk of hypoxaemia (low oxygen concentration in the blood).
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The cramped conditions and long periods of being less active on a flight can cause pain, stiffness or swelling of your legs. Being less active can lead to slow blood flow in your veins which increases your risk of developing a blood clot, known as deep vein thrombosis (DVT). DVTs most commonly form in the legs.
According to a review in 2022, combining data from 18 studies, the longer you travel, the greater the risk of blood clots. The authors calculated there was a 26% higher risk for every two hours of air travel, starting after four hours.
Sitting on a plane for many hours not only allows blood to pool, but it also puts your knees at an angle that makes the veins inside them kink up. Just as water doesn't flow easily through a kinked-up garden hose, blood can't flow as well through a vein that has a kink.