Furthermore, a change in airplane cabin pressure can also affect bladder function. Therefore, consuming less liquid will avoid putting pressure on the bladder. If possible, don't drink anything for at least two hours before take-off.
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Just like a bag of peanuts mid-flight, air pressure changes will cause you to inflate. A build-up of gas can lead to bloating, constipation and stomach pains. Lack of movement leads to fluid build-up around the body, increasing the risk of deep vein thrombosis (DVT).
Air pressure is lower at higher altitudes, which means your body takes in less oxygen. Airlines “pressurize” the air in the cabin, but not to sea-level pressures, so there's still less oxygen getting to your body when you fly, which can make you feel drained or even short of breath.
If you don't shower and bacteria and fungi do catch a ride back to your hotel with you, Tetro says you may end up depositing germs that aren't your own into your new space—particularly your bed.