Schedule and frequency. The Milan metro runs every day from 6 am until 12:30 am (midnight). On 25 December and 1 May, the metro opens from 7 am until 7:30 pm. The frequency of the Milan Metro depends on the time of day, on the line, and the day of the week, but generally, the trains arrive every 2-4 minutes.

No, the Milan Metro (Metropolitana di Milano) does not run 24 hours a day. On a standard schedule in 2026, the lines (M1, M2, M3, and M5) typically operate from approximately 5:30 AM until about 12:30 AM. On special occasions or during major events like Milan Fashion Week or the Salone del Mobile, service may be extended until 1:30 AM or 2:00 AM. For those needing to travel in the middle of the night, Milan provides an extensive "NM" Night Bus network. These buses (labeled NM1, NM2, and NM3) follow the exact routes of the metro lines above ground and run every 30 minutes until the metro restarts in the morning. Additionally, the newer M4 "Blue Line" connecting to Linate Airport follows similar operational hours. If you are staying out late in the Navigli or Brera districts, you will need to rely on these night buses or ride-sharing apps like Uber and FreeNow, as the underground stations remain closed and locked after the final midnight trains have departed.