As of 2026, Resorts World Las Vegas maintains a strict policy that prohibits smoking in almost all indoor areas, including the hotel rooms, corridors, and most public walkways. Following the trend of "smoke-free" hospitality on the Strip, the resort was designed with advanced air filtration systems to ensure a fresh environment. However, like many major Nevada properties, smoking is still permitted in designated areas of the casino floor. Guests are generally allowed to smoke while actively gambling at slot machines or select table games, though specific "non-smoking" sections are clearly partitioned. Vaping follows the same regional restrictions as traditional tobacco. If a guest is found smoking in a non-smoking hotel room, the resort typically levies a significant cleaning fee (often upwards of $500). For those who prefer a completely smoke-free gaming experience, the nearby Park MGM remains the only major Strip resort to be 100% smoke-free throughout its entire facility, while Resorts World offers a "hybrid" approach to cater to both demographics.