Medication is usually screened by X-ray; however, if a passenger does not want a medication X-rayed, he or she may ask for a visual inspection instead. This request must be made before any items are sent through the X-ray tunnel.

Yes, TSA officers have the authority to inspect all items in your carry-on and checked luggage, including medication. While TSA does not generally require you to keep your medication in its original prescription bottles for domestic flights, they may scrutinize loose pills or "pill organizers" if they appear suspicious. In 2026, enhanced 3D CT scanners allow TSA to identify different densities of materials more effectively, which may trigger a manual bag check if a large quantity of pills is detected. To ensure a smooth process, it is recommended to keep medications in their original pharmacy-labeled containers, carry a copy of your prescription, and declare any liquid medications over 3.4 ounces at the start of the screening process. For international travel, many countries are much stricter than the US, and having original packaging is often a legal requirement to avoid confiscation or legal issues.