Like humans, dogs can get altitude sickness, though it is much less common. Symptoms include vomiting, excessive drooling, panting, ear discomfort and lethargy. In extreme cases, it can cause a build up of fluid in the lungs and brain.
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Your dog will get acclimated in a few days to high altitude. However, if you find that he has not acclimated and continues to display signs of altitude sickness, then take him to a lower elevation as soon as possible. If symptoms don't abate, then schedule a vet visit.
Be sure to gradually increase your dog's exposure to higher altitudes by starting lower and taking short hikes at progressively higher elevations over the course of several weeks. If your dog is adjusting well, increase the distance in the same manner.
Dogs may struggle to cope with the stress and discomfort of long flights. It's important to ensure they have plenty of food and water, as well as opportunities to stretch their legs and relieve themselves. Additionally, providing toys or familiar items from home can help provide comfort and reassurance.