To prevent getting a cold on a plane in 2026, you should prioritize a combination of hygiene and strategic seating. Research suggests that a window seat is the healthiest choice, as it minimizes your proximity to the steady flow of passengers and crew walking down the aisle, which reduces your exposure to airborne droplets. You should also utilize alcohol-based disinfectant wipes (at least 60% alcohol) to thoroughly clean your immediate area, including the tray table, armrests, and seatback pocket. Keep the overhead air vent open and directed slightly in front of your face; this creates a "curtain" of filtered, HEPA-purified air that can help blow away stagnant germs. Staying hydrated is vital, so drink plenty of water and consider adding electrolytes to support your immune system's barrier functions. Finally, frequent handwashing—or using hand sanitizer after touching communal surfaces like the overhead bin or lavatory door—is your primary defense against the self-inoculation that occurs when you inadvertently touch your eyes, nose, or mouth during the flight.