Once you're inside, assemble your supplies — diaper, wipes, and disposal bag — next to the sink and layer some paper towels or a changing pad on the closed toilet seat. Place your child on the seat, whip off the dirty diaper, stick it in an airsick bag or plastic bag, and dispose of it in the garbage.

Changing a diaper on a plane requires a bit of "aero-logistics" due to the cramped quarters. Most commercial aircraft have at least one lavatory equipped with a fold-down changing table, usually located directly above the toilet. You can check for a small icon on the outside of the bathroom door or ask a flight attendant which lavatory is "baby-friendly." Before heading to the back, prep a small "go-bag" with just one diaper, a travel pack of wipes, and a disposable scented bag, as there is no room for a full diaper bag. Once inside, lower the table and use a portable changing pad or a paper towel as a barrier. Be prepared for the loud "vacuum flush" sound, which can startle infants. When finished, place the dirty diaper in a scented disposal bag before putting it in the trash bin to be mindful of the shared air in the cabin. Never change a baby on the tray table at your seat; this is considered a major health and etiquette violation, as those tables are used for food and are not sanitized between flights for biological waste.