The Trenord train service of the Milano - Saronno - Como lake railway line connects Milan to Como lake in about 60 minutes. From Como Lake first train departs at 5:16, the last one at 22:16. From Milan the first train departs at 5:43, th last one at 22:43. From Como lake to Milan Trenord 2nd class ticket is 4,80€.

Trains from Milan to Lake Como (specifically to the Como San Giovanni or Como Lago stations) run quite late, making a day trip or a late-night arrival very feasible. In 2026, the final trains typically depart from Milan Centrale or Milan Cadorna between 11:00 PM and 11:30 PM. The journey is short, usually taking between 40 to 60 minutes depending on the service. It is important to distinguish between the two main routes: the Trenitalia line to San Giovanni (on the main line to Switzerland) and the Trenord line to Como Lago (which drops you right at the water's edge). While the trains run late, the ferries and local buses within Lake Como usually stop operating much earlier, often around 8:00 PM or 9:00 PM. If you arrive on the midnight train, you should be prepared to walk to your hotel or pre-book a taxi, as ride-share services like Uber are less prevalent in the Como area than in central Milan. Always check the "Trenitalia" or "Trenord" apps on the day of travel, as maintenance work—common on the Italian rail network in 2026—can occasionally move the final departure to an earlier time or replace it with a bus.