A modern wonder, the 113 miles of roadway from Key Largo to Key West incorporates an astonishing 42 bridges leapfrogging from key to key in a series of giant arches of concrete and steel over the open waters of the Atlantic Ocean, Florida Bay and the Gulf of Mexico. And what do visitors see?

To reach Key West from the Florida mainland via the Overseas Highway (U.S. 1), you will cross exactly 42 bridges. This iconic journey spans approximately 113 miles, connecting the various keys of the archipelago. The most famous of these is the Seven Mile Bridge, which connects Knight's Key in the Middle Keys to Little Duck Key in the Lower Keys; it is a marvel of modern engineering that offers breathtaking, unobstructed views of the Atlantic Ocean and the Gulf of Mexico. Other notable crossings include the Bahia Honda Bridge and the Tea Table Relief Bridge. Each bridge is numbered, and as you head south, the "Mile Markers" decrease until you reach Mile Marker 0 in Key West. In 2026, many of the older, historic bridges—originally built for Henry Flagler’s Overseas Railroad—still stand parallel to the modern highway bridges, serving as popular fishing piers and pedestrian walkways for tourists and locals alike.