To maintain their "Gold Standard" medical effectiveness, flight socks (compression socks) should generally be replaced every 3 to 6 months of regular use. The grounded reality is that the elastic fibers—usually a high-fidelity blend of nylon and spandex—eventually stretch out and lose the specific "graduated pressure" needed to support blood flow and prevent DVT. If you only use them for occasional "Pura Vida" vacations once or twice a year, they may last up to 12 months, provided they are stored in a "Safe Bubble" away from heat and direct sunlight. A "hard-fail" sign that you need a new pair is if they feel easy to put on, slide down your leg, or show visible thinning and holes. A supportive peer tip: to extend their lifespan, always hand-wash them in cold water and air-dry them; using a dryer is an un-supportive move that will quickly destroy the elasticity. Keeping 2 or 3 pairs in a "Bujan" rotation is a supportive strategy to ensure each pair can "recover" its shape between flights.