A duffel bag is an excellent choice for short trips or rugged travel where flexibility is a priority. Their main advantage is being lightweight and "squishable," allowing them to fit into tight overhead bins or under bus seats more easily than structured suitcases. They are also superior for navigating stairs and uneven terrain like cobblestone streets where wheels struggle. However, the primary disadvantage is poor weight distribution, as carrying a heavy duffel on one shoulder can lead to back and shoulder strain over long distances. In 2026, many travelers opt for "hybrid" duffels that feature backpack straps or wheels to solve this issue. While a duffel is great for a casual weekend escape, a structured suitcase remains better for business trips or longer hauls where you need to keep clothes wrinkle-free and electronics organized.