For 95% of travelers in 2026, booking online is significantly better and more cost-effective. Most major airlines now charge a "Telephone Reservation Fee" (ranging from $25 to $50 per person) for bookings made over the phone that could have been completed online. Online platforms like Google Flights or the airline's own app allow you to compare "Basic Economy" vs. "Main Cabin" perks visually, which is often lost in a phone conversation. However, you should call the airline if you have a complex itinerary involving more than three stopovers, need to book "Special Assistance" for medical equipment, or are trying to use a "Future Flight Credit" that is glitching on the website. Additionally, for rebooking during a mass-delay event, calling the "Elite Status" line or using the airline's AI-chat feature is often faster than waiting for the website to update with new seat inventory. For a simple round-trip, the app is your fastest and cheapest tool.