Travelers to Mexico are warned to be aware of the inherent risk of contracting and spreading the virus by visiting the area. The CDC recommends that all tourists to Mexico be fully vaccinated and follow local health and safety protocol such as mask wearing and social distancing.

As of March 2026, cruising to Mexico is generally considered safe, though some itineraries have seen recent adjustments. In late February 2026, some cruise lines like Norwegian, Princess, and Holland America rerouted ships or canceled stops in Puerto Vallarta due to localized security operations and unrest in the state of Jalisco. However, industry experts and major ports like the Port of San Diego emphasize that these changes are proactive safety measures and that the ships themselves remain highly secure environments. Other popular destinations like Cabo San Lucas and Mazatlán are currently reporting normal operations with no significant disruptions. On the Caribbean side (Cozumel and Costa Maya), travel continues as usual. The U.S. Department of State provides state-specific advisories for Mexico, so it is wise to check the current "Level" for your specific ports. Most travelers find that sticking to organized excursions and staying within tourist zones ensures a safe experience, as cruise lines will not dock in any area where they cannot guarantee passenger safety.