For the city of Florence itself, the answer is a firm "No." The historic center of Florence is small, incredibly walkable, and mostly designated as a ZTL (Zona a Traffico Limitato). If you accidentally drive into these restricted zones without a local permit, you will be caught by automated cameras and face hefty fines of €80 to €300 per entry. Additionally, parking in the city is notoriously difficult and expensive, often costing €30–€50 per day. However, if Florence is your base for exploring the Tuscan countryside—places like San Gimignano, Montepulciano, or the Chianti vineyards—then renting a car is highly worth it and essentially the only way to see these remote areas at your own pace. A grounded strategy for 2026: do your sightseeing in Florence on foot for 2–3 days, and then pick up your rental car from the Florence Airport (FLR) or a rental agency on the outskirts of the city center. This allows you to head straight to the hills of Tuscany without the stress of navigating Florence's narrow, one-way streets and high-risk "Limited Traffic Zones."