The metro opens every day from 5:30 am to 11:30 pm. On Friday and Saturday, the metro runs until 1:30 am.
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The first train from each end of the metro lines (see map) is 5.30am every day. The last train leaves from the ends of the metro at 11.30pm on weeknights, and 1.30am on a Friday and Saturday night. That means if you're in the center and it's just after 11.30/1.30 you may still be able to catch your metro.
MetroBus 24 hoursThis ticket allows unlimited public transportation from the moment the ticket is validated until midnight of the same day. The MetroBus 24 hours costs € 7 ( US$ 7.50).
Trains operate between 5:30 am until 23:30 (11:30 pm) from Sunday till Friday.On Saturdays, the system closes at 00:30 (12:30 am). Trains visit a station every 5 - 10 minutes, depending on a weekday vs. weekend.
The easiest and quickest way to reach the Vatican Museums would be to take the Metro. Line A of the Metro will take you to Ottaviano-S.Pietro station, which is located right outside Vatican City.
Rome bus, tram & Metro fares & ticketsTickets for both the bus system and Metro can be purchased from tobacconists, bars, or vending machines at Metro stations and major bus stops. On both buses and metro there is a flat fare, whether you go one stop or to the end of the line.
Info & Tickets Pantheon RomeSince July 3, 2023, the Pantheon can no longer be visited for free. Pantheon tickets cost 5 euros. These tickets can be bought at the entrance of the Pantheon or online reservations at museiitaliani.it (typically Italian: this website does not work when the tickets are introduced...)
The Leonardo Express is a Trenitalia train connecting Fiumicino airport with the main train station in Rome, Termini. It takes roughly 32 minutes and leaves the airport every half-hour, or every 15 minutes during peak hours. It's non-stop service from the airport to Termini.
Rome is a walkable city and most of its top attractions are close together in car free zones. One of the best ways to explore Rome is on an orientation city tour, as part of a guided holiday, with an expert local guide.
Rome bus, tram & Metro fares & ticketsYou have to purchase your tickets before you board any public transport in Rome. Most people will have a pass of one kind or another. Tickets for both the bus system and Metro can be purchased from tobacconists, bars, or vending machines at Metro stations and major bus stops.
The Vatican City is free to enter, allowing you to meander the likes of St. Peter's Basilica and St. Peter's Square without dropping a dime. However, if you want to see the Vatican's starring attractions: the Sistine Chapel and Vatican Museums, you will have to pay around 15 Euros.