Yes, in 2026, you can take a spectacular "Full Transit" cruise from Los Angeles to Miami, typically via the Panama Canal. These are "repositioning" or specialty cruises that usually last between 15 and 21 nights. Major lines like Norwegian (NCL), Princess, and Celebrity offer these routes, often departing in the spring or autumn as ships move between their Alaskan and Caribbean seasons. A typical 19-night itinerary on a ship like the Norwegian Bliss might include stops in Cabo San Lucas, Puerto Quetzal (Guatemala), and Cartagena (Colombia), with the highlight being the daylight transit through the historic Panama Canal locks. These cruises are highly sought after by "slow travelers" because they offer a mix of relaxing days at sea and diverse cultural stops across Central and South America. Because they are longer voyages, they often attract a more mature crowd and provide a more "classic" cruising atmosphere compared to the standard 7-night Caribbean loops. Prices in 2026 vary, but booking a year in advance is recommended to secure a balcony cabin for the canal crossing.