There are 5 ferry companies with a combined offering of 15 ferry routes connecting Heraklion to Santorini (Thira), Milos, Mykonos, Paros, Naxos, Tinos, Syros, Anafi & Ios, Chania to Milos, Sitia to Santorini (Thira), Anafi & Milos, Rethymno to Santorini (Thira) & Agios Nikolaos to Santorini (Thira).
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Island hopping from CreteYou can catch a ferry from Crete to other islands in Greece and explore the microcosm of the Aegean Islands. During the summer there are ferries from Crete to Santorini and Mykonos, with daily departures from Heraklion. You can also catch a ferry from Rethymno to popular Cycladic destinations.
Day trips to Santorini from Crete, Naxos, Paros, and other Greek islands are usually not worth the time and effort. Staying on Santorini for several nights is awesome. Visiting for a few hours in the middle of the day (on a day trip) is busy – though still definitely worth it for many visitors.