Yes, Uber operates 24 hours a day, 7 days a week in Orlando, Florida. As a massive global tourism hub, Orlando has a high density of drivers who cater to late-night arrivals at Orlando International (MCO) and the shifting schedules of theme park workers and visitors. In 2026, Uber remains a high-value alternative to the more expensive hotel shuttles or traditional taxis. A peer-to-peer strategy for 2026 is using Uber Reserve, which allows you to book a ride up to 90 days in advance—perfect for those "must-make" 4:00 AM airport runs. While availability is constant, you should expect "Surge Pricing" during peak times, such as when Magic Kingdom closes or during major conventions at the Orange County Convention Center. For the budget-conscious, the Lynx Bus Route 111 is the cheapest way to get from MCO to the Disney area for just $2, but for convenience and door-to-door service at any hour, Uber remains the undisputed "go-to" for both locals and tourists in the City Beautiful.