Should I take aspirin before a flight?

Talk to your doctor about wearing compression stockings or taking medicine before departure if you have additional risk factors for blood clots. Taking aspirin to prevent blood clots when traveling is not recommended. If you take aspirin for other reasons, check with your doctor.



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Aspirin? Taking 75mg (a quarter of a normal 300mg tablet) some hours before your flight may reduce your chances of a DVT slightly (but remember that Aspirin can sometimes cause indigestion in people with a tendency to it, if in doubt ask your GP);

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Your GP will not be able to advise on the use of anticoagulants for flying as it is a specialist issue, so allow plenty of time to get an opinion from your specialist. Note: aspirin is not used to prevent DVT.

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?Preventive Measures
  1. Move around as much as possible.
  2. Choose an aisle seat where feasible as this is known to encourage moving around during the journey .
  3. Carry out calf muscle exercises: ...
  4. Try to avoid placing cabin baggage where it can restrict your leg movement.


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Blood clots can sometimes form in your legs during air travel because you are immobile for long periods of time, often sitting in cramped spaces with little leg room. The clinical term for this type of blood clot is deep vein thrombosis (DVT). The longer the flight, the more at risk you are for developing a clot.

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Even if you travel a long distance, the risk of developing a blood clot is generally very small. Your level of risk depends on the duration of travel as well as whether you have any other risks for blood clots.

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Symptoms of DVT may be silent or present as a deep pain in one calf or thigh (with swelling). PE may also be silent but symptoms may include sharp chest pain, breathlessness, bloody sputum, and cardiac collapse in some cases. DVT or PE may manifest during or shortly after the flight, but often not for several weeks.

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Talk to your doctor about wearing compression stockings or taking medicine before departure if you have additional risk factors for blood clots. Taking aspirin to prevent blood clots when traveling is not recommended.

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Research has shown that wearing compression socks during long-haul flights can significantly reduce the risk of developing blood clots and alleviate symptoms of leg fatigue and discomfort.

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Air travel increases the risk of developing blood clots in the veins of the legs, which can then enter the bloodstream and block an artery in the lungs, a condition called pulmonary embolism. In some cases, the opening can allow the blood clot to enter the arteries of the brain, causing a stroke.

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The plasma half-life of aspirin is only 20 minutes; however, because platelets cannot generate new COX, the effects of aspirin last for the duration of the life of the platelet (˜10 days). After a single dose of aspirin, platelet COX activity recovers by ˜10% per day as a function of platelet turnover.

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