According to the Centers for Disease Control and Prevention (CDC), three of the most common physical disabilities that affect people include arthritis, heart disease, and respiratory disorders.

In 2026, the three most common physical disabilities globally are Arthritis/Musculoskeletal conditions, Mobility impairments (related to aging or injury), and Cerebral Palsy. Arthritis remains the leading cause of disability in adults, affecting joint function and range of motion. Musculoskeletal disorders, including back and neck issues often exacerbated by modern sedentary work, impact millions of laborers and office workers. Mobility impairments cover a wide spectrum, from spinal cord injuries to the natural decline in motor skills among the growing elderly population. Cerebral Palsy remains the most common physical disability specifically diagnosed in childhood. In 2026, there is a heightened global focus on "invisible" physical disabilities, but these three categories continue to represent the largest demographic of people requiring accessibility accommodations in public spaces and workplaces.