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What can I take for sinus congestion before flying?

If you have sinus pressure during flights then you should bring along a decongestant spray (Oxymetazoline or Phenylephrine), found in the nasal aisle at the drug store, and use it approximately one hour before a flight of any duration.



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1. About one hour before expected descent, take a decongestant (such as Sudafed- 12hr). 2. About 30 minutes before the flight use a nasal spray (such as Afrin or Neo-Synephrine).

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Topical Decongestants We recommend using a topical decongestant 30 minutes before your flight, allowing time for it to get to work before takeoff.

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Avoid overuse, however, because nasal sprays taken over three to four days can increase congestion. Use decongestant pills cautiously. Decongestants taken by mouth might help if taken 30 minutes to an hour before an airplane flight.

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With a doctor's approval, adults can take a decongestant. “If it's a short flight, take it [the decongestant] before leaving,” House says. If it's a long flight, eight hours or so, you might take it an hour or so before the scheduled landing.

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If you start to notice this pressure building, you can try some of these strategies:
  1. Take an antihistamine if needed before your flight. ...
  2. Yawn or swallow during takeoff.
  3. Try chewing a piece of gum or candy during takeoff, if yawning and swallowing don't work for you.


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The dry air, low pressure, and the low amount of oxygen cause the immune system to weaken and can lead to inflamed sinus cavities. This, in addition to being confined in a small area with little airflow, makes it hard to avoid getting sinusitis from another sick passenger.

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What medication is used to make flying easier? Common over-the-counter medications used for flying anxiety are Dramamine, Ambien, and Benzodiazepines like Xanax. Natural medications include GABA supplements and Melatonin supplements or gummies.

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Take 1 Sudafed tablet on the morning of flight. Take 1 Sudafed tablet about 2 hours before landing. Spray nose with Otrivine well about 1 hour and then again 30 minutes before landing. Try to clear nasal ear passage by holding nose, blow out cheeks with mouth closed and swallow.

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Infectious Diseases
An airline can deny boarding of any passenger who looks unwell, especially if they suspect the passenger might be infectious (infect other passengers).

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When the plane changes elevation during descent and ascent the sinuses must equilibrate to match the air pressure in the cabin but when the sinuses and eustachian tubes are blocked equilibration can be an issue. The pain occurs because of the restriction of air flow causing pressure in our sinuses.

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With the right preparation, your in-flight experience can be allergy-free and clear for landing before you leave the ground. So, to help keep the friendly skies friendly, be sure to use your favorite FLONASE allergy relief nasal spray the morning of your flight.

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Try taking a decongestant or a nonsteroidal anti-inflammatory medicine before you get on the airplane, particularly if you are suffering from a head cold or swollen sinuses. If you have high blood pressure or heart problems, you should not take decongestants without approval of your healthcare provider.

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