What drugs are used to relax while traveling?

Two types of medication often used to reduce travel-related anxiety are benzodiazepines and selective serotonin reuptake inhibitors (SSRIs). 1 Benzodiazepines reduce anxiety fairly quickly by slowing the central nervous system while SSRIs take a bit longer to work as they block serotonin reabsorption.



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Physicians can prescribe medications as needed for flight anxiety. The most common class includes benzodiazepines like Xanax and Ativan, which are relatively fast-acting to relieve anxiety and stay in the body for several hours, which is the duration for most cross-country flights.

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People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.

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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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“Beta-blockers work to dampen down the body's 'fight-or-flight' response,” Dr. Owens explains. “Often, when people think of anxiety or a panic attack, it's accompanied by a racing heart, sweating or shaking. Beta-blockers can work by lessening those symptoms.”

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For example, deep breathing or meditation during take-off, landing or turbulence can reduce your symptoms of anxiety. You can also learn to “talk back” to negative thoughts about flying when they arise.

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Preparing for anxiety before your flight
  1. Don't drink coffee on the day of the flight.
  2. Wear compression socks.
  3. Get cosy.
  4. Get a good neck pillow.
  5. Bring earplugs and an eye mask.
  6. Do some research about your particular flight anxiety.
  7. Choose a good seat.
  8. Watch calm movies.


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People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.

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So many travelers struggle with this fear, so the best way to cope is to find a seat with plenty of space. The least crowded section of the plane is first or business class. But if upgraded flying isn't in your budget there are still options. Try sitting in an aisle seat in an exit row towards the front of the plane.

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Travel anxiety is the fear of visiting an unfamiliar place. It can also involve the stress that comes with planning your travels. Even if you have no history of anxiety, the idea of being outside familiar territory can throw you into panic mode.

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Aerophobia is a fear of flying. It's very common, affecting more than 25 million adults in the U.S. Psychotherapy can usually help people overcome their fear and fly without extreme anxiety or panic attacks.

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Try sitting in an aisle seat in an exit row towards the front of the plane. These seats typically have more legroom, are easier to get out of, and also reduce the number of other passengers in your view, making the space feel less crowded.

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