The last such eruption at Popocatepetl was around A.D. 800. The eruption destroyed nearby settlements and culminated in mudflows that blanketed the Puebla Valley. An eruption of this magnitude today would endanger hundreds of thousands of lives.
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Yellowstone Supervolcano (Wyoming, United States) Effects of a major eruption: When the Yellowstone Caldera, or supervolcano, in Yellowstone National Park erupts again, its effects would be worldwide, the U.S. Geographical Survey said.