What is the best drug to take when flying?

Pharmacological treatment These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).



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Flight anxiety medication
  • fluvoxamine (Faverin)
  • citalopram (Celexa)
  • escitalopram (Lexapro)
  • paroxetine (Paxil)


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What Are the Best—And Safest—Sleeping Pills for Flights?
  • Ambien. Ambien—the most powerful option on this list and the only one that requires a prescription—works as a sedative-hypnotic medication that slows your brain activity to make you feel very sleepy. ...
  • Tylenol PM. ...
  • Melatonin.


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What Are the Best—And Safest—Sleeping Pills for Flights?
  • Ambien. Ambien—the most powerful option on this list and the only one that requires a prescription—works as a sedative-hypnotic medication that slows your brain activity to make you feel very sleepy. ...
  • Tylenol PM. ...
  • Melatonin.


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Take Dramamine If you know you're prone to motion sickness or nausea in other forms of travel, make sure to pack Dramamine®. It actually prevents nausea, dizziness, and vomiting.

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For example, deep breathing or meditation during take-off, landing or turbulence can reduce your symptoms of anxiety. You can also learn to “talk back” to negative thoughts about flying when they arise.

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Exposure therapy: This type of therapy gradually exposes you to places, thoughts or situations that relate to air travel. You may visit an airport and watch planes arrive and depart. Virtual reality tools, such as computer simulations of flights, can also help you overcome your fear of flying.

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Xanax, a member of the same pharmaceutical family (benzodiazepines) as diazepam, is a strong one. Take it about two to three hours before you fly, and do not mix it with alcohol. There is a risk of dependency, though, with these benzodiazepines, but only if you are taking them more than once a week.

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While Xanax may be useful for flying on an airplane, it will not help you with your anxiety. It may help in the moment but you will not tackle your fear of flying if you are asleep the whole flight. If you ran out of your medication or left it at home, the anxiety will still exist if you go on an airplane again.

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Initial use of benzodiazepines, including the well-known Diazepam also known as 'Valium', was enthusiastic and they were hailed as a wonder drug.

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Flight attendants are trained in first aid – and this covers panic attacks and supporting people with anxiety on a flight. This training includes the questions they should ask someone having a panic attack and how to manage you out of one.

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Taking CBD is non-addictive, and thousands of people use it to deal with stress and anxiety on a daily basis. This is why CBD is a great solution for flight anxiety. Stress and anxiety are very common feelings when traveling or flying.

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Doctors rarely recommend sleeping tablets for flying for several reasons. Some tablets render you immobile, which would be problematic during an in-flight emergency. Even if you're OK with that small risk, avoid sitting near an emergency exit where you could be responsible for many lives in an emergency.

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Lunesta (eszopiclone) and Sonata (zaleplon) are other well-known prescription sleeping pills for travel. They act quickly, but won't keep you asleep as long as Ambien CR. Sonata is especially recommended for those on flights of only five to six hours.

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