What is the best medicine to relax on a plane?

Physicians can prescribe medications as needed for flight anxiety. The most common class includes benzodiazepines like Xanax and Ativan, which are relatively fast-acting to relieve anxiety and stay in the body for several hours, which is the duration for most cross-country flights.



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These drugs are usually taken shortly before a flight. They include: Anti-anxiety medication, such as diazepam (Valium) or alprazolam (Xanax). Motion sickness medication, such as dimenhydrinate (Dramamine).

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Distract yourself with a good book or movie Engrossing yourself in a good book, movie, or TV show may be an effective way to escape your own mind. Download something to watch before your flight, check the in-flight entertainment, or bring along something interesting to read.

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8 Steps to Overcoming Your Fear of Flying
  1. Latch on to triggers that set you off. ...
  2. Step onto the airplane with knowledge. ...
  3. Anticipate your anxiety. ...
  4. Separate fear from danger. ...
  5. Recognize that common sense makes no sense. ...
  6. Smooth over things that go bump in the flight. ...
  7. Educate fellow fliers how to help you. ...
  8. Value each flight.


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People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.

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Understanding Triggers And someone who fears heights might become terrified thinking about flying many miles above the ground. The list of triggers is long: turbulence, take-off, landings, terrorism, crashes, social anxieties, or being too far from home.

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Medications for flight anxiety, like SSRIs and SNRIs, can help manage symptoms in addition to other treatments, like exposure therapy and CBT. Some medications can also help you with upsetting and sudden symptoms, including episodes of panic. It's best to talk with a doctor about your options for flight anxiety.

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Try antihistamines: For those with allergy symptoms and air pressure regulation difficulties, medications like Claritin, Zyrtec, or Allegra may be a good option. Antihistamines are often formulated to include decongestants (such as Claritin-D, Allegra-D, and Zyrtec-D).

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By staying awake, you can practice the methods below to help eliminate or reduce pain and pressure. If you have any allergy or cold-related symptoms, make sure you take an antihistamine or decongestant spray at least 30-45 minutes before your flight.

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You can help send a signal to your brain that it's time to sleep by using melatonin. Melatonin is a more natural alternative to a prescription sleep aid, and it's available at drugstores over the counter. Maloney travels with Sleep Now, a brand that features melatonin and chamomile to help travelers relax.

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Diazepam is a sedative. This means, the medication makes you sleepy and more relaxed. If there would be an emergency during the flight, this could impair your ability to concentrate, follow instructions, or react to the situation. This could seriously affect the safety of you and the people around you.

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Take it about two to three hours before you fly, and do not mix it with alcohol. There is a risk of dependency, though, with these benzodiazepines, but only if you are taking them more than once a week.

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