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What is the best over-the-counter medication for travel sickness?

The first is antihistamines, both prescription and over-the-counter. These are the most commonly used medications for motion sickness, and they're available in any drug store and in many supermarkets. Cyclizine (Marezine) and dimenhydrinate (Dramamine) are two major ones. Make sure to read the drug labels, though.



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Nutrition and Dietary Supplements
  • Avoid spicy, greasy, or fatty meals.
  • DO NOT overeat before traveling.
  • Drink plenty of water.
  • Dry crackers and carbonated sodas (such as ginger ale) help some people avoid nausea.
  • People who tend to have motion sickness may want to eat small, frequent meals.


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The first is antihistamines, both prescription and over-the-counter. These are the most commonly used medications for motion sickness, and they're available in any drug store and in many supermarkets. Cyclizine (Marezine) and dimenhydrinate (Dramamine) are two major ones.

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People who do not travel often may get used to movement during a trip lasting several days. Even those who travel often may find that symptoms get better as they are more often exposed to motion. However, people who get anxious before a journey often have worsened symptoms of motion sickness.

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