What is the best over the counter medicine for fear of flying?

Many individuals find L-theanine helpful in reducing anxiety and promoting a sense of well-being during their flight. It's important to note that while these medications are available over-the-counter, it's still advisable to consult with a healthcare professional before using them for flight anxiety.



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People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.

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If you know you're prone to aviation headaches, take a non-steroidal anti-inflammatory agent (i.e. ibuprofen) one to two hours before takeoff to get ahead of any inflammation or pain.

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Take a decongestant before your flight. Reducing congestion will help prevent ear barotrauma (airplane ear). Remember to swallow and yawn during plane takeoff and landing. This helps your eustachian tubes open.

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People often come to us requesting the doctor or nurse to prescribe diazepam for fear of flying or assist with sleep during flights. Diazepam is a sedative, which means it makes you sleepy and more relaxed.

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OTC alternatives
  • 5-Hydroxytryptophan (5-HTP): 5-HTP is a supplement that helps increase serotonin levels. ...
  • Antihistamines: Antihistamines, such as diphenhydramine (Benadryl), are taken off-label to address short-term sleep problems in people with anxiety.


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If you start to notice this pressure building, you can try some of these strategies:
  1. Take an antihistamine if needed before your flight. ...
  2. Yawn or swallow during takeoff.
  3. Try chewing a piece of gum or candy during takeoff, if yawning and swallowing don't work for you.


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By staying awake, you can practice the methods below to help eliminate or reduce pain and pressure. If you have any allergy or cold-related symptoms, make sure you take an antihistamine or decongestant spray at least 30-45 minutes before your flight.

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The good news is that some studies (study links, a and b) have identified how magnesium may ease certain symptoms of stress and anxiety. Here are the facts: Magnesium may help to control the chemical messengers (neurotransmitters) in the brain, resulting in a calming effect on the body.

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