What is the best over the counter medicine for flight anxiety?

Dramamine, a flight anxiety medication over the counter typically used to fight motion sickness, can perform double duty as an anxiety reliever for air travel. Medicine for flight anxiety over the counter, like Dramamine, is usually recommended for nervous flyers.



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Take a decongestant before your flight. Reducing congestion will help prevent ear barotrauma (airplane ear). Remember to swallow and yawn during plane takeoff and landing. This helps your eustachian tubes open.

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The two main medication classes most often prescribed are:
  • Benzodiazepines, such as the antianxiety drugs alprazolam (Xanax®), clonazepam (Klonopin®) and diazepam (Valium®).
  • Selective serotonin reuptake inhibitors, such as paroxetine (Paxil®) or escitalopram (Lexapro®).


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Low vitamin D levels are associated with increased symptoms of depression and anxiety. For this reason, vitamin D screening should be performed in the prevention and treatment planning of these mood disorders.

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